When the Muppets graduate from Danhurst College, they take their song-filled senior revue to New York City, only to learn that it isn't easy to find a producer who's willing to back a show starring a frog and a pig. Of course, Kermit the Frog and Miss Piggy won't take no for an answer, launching a search for someone to take them to Broadway.
Kermit the Frog is persuaded by agent Dom DeLuise to pursue a career in Hollywood. Along the way, Kermit picks up Fozzie Bear, Miss Piggy, Gonzo, and a motley crew of other Muppets with similar aspirations. Meanwhile, Kermit must elude the grasp of a frog-leg restaurant magnate.
When Billy Peltzer is given a strange but adorable pet named Gizmo for Christmas, he inadvertently breaks the three important rules of caring for a Mogwai, and unleashes a horde of mischievous gremlins on a small town.
Kermit and Fozzie are newspaper reporters sent to London to interview Lady Holiday, a wealthy fashion designer whose priceless diamond necklace is stolen. Kermit meets and falls in love with her secretary, Miss Piggy. The jewel thieves strike again, and this time frame Miss Piggy. It's up to Kermit and Muppets to bring the real culprits to justice.
In a world where human beings and puppets live together, when the members of the cast of a children's television show aired during the 1990s begin to get murdered one by one, puppet Phil Philips, a former LAPD detective who fell in disgrace and turned into a private eye, takes on the case at the request of his old boss in order to assist detective Edwards, who was his partner in the past.
When teen Sarah is forced to babysit Toby, her baby stepbrother, she summons Jareth the Goblin King to take him away. When he is actually kidnapped, Sarah is given just thirteen hours to solve a labyrinth and rescue him.
When the girl that detective Joe Hallenback is protecting gets murdered, the boyfriend of the murdered girl attempts to investigate and solve the case. What they discover is that there is deep seated corruption going on between a crooked politician and the owner of a pro football team.
While on a grand world tour, The Muppets find themselves wrapped into an European jewel-heist caper headed by a Kermit the Frog look-alike and his dastardly sidekick.